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Dcc^{Tn(sb-T2/Bart3)2.205Mcwi}

Insertion Overview

UCSC Blat Alignment
Insertion Location:	intron 1
5' Flanking Sequence:	TATCACCCAGAGGGGCTGTCCAATGATACAGATTTTTTTTTTGGAATCTTTGATGCTTct ag

Gene
***Rat Entrez Gene If Available; Else Human or Mouse

Symbol:	Dcc
Name:	deleted in colorectal carcinoma
Synonyms:	N/A
Chromosome:	N/A

Mouse Allele

MGI	Symbol	Name	Type
MGI:2446481	Dcc^kanga	kanga	Spontaneous
MGI:1934924	Dcc^tm1Wbg	targeted mutation 1, Robert A Weinberg	Targeted (knock-out)

Associated Diseases

Disease	Disease Class	Sub Category
Colon Cancer	Cancer Targets	Tumors of the Digestive System
Esophagel Carcinoma	Cancer Targets	Tumors of the Digestive System
Colon Cancer	Gastrointestinal system	Tumors of the Digestive System

Gene Ontology Function Process Component

GO	Term	Evidence	Pubmed
GO:0003713	transcription coactivator activity	IMP	12840034
GO:0005042	netrin receptor activity	IMP	8861902
GO:0005515	protein binding	IEA
GO:0005515	protein binding	ISS

Homologene Orthology (Human/Mouse)

Taxon	Symbol	Synonyms	Chromosome
human	DCC	CRC18\|CRCR1\|IGDCC1	N/A
mouse	Dcc	C030036D22Rik\|Igdcc1	N/A

Related Links

Rat Model Source

Medical College of Wisconsin