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Dnah11^{Tn(sb-T2/Bart3)2.293Mcwi}

Insertion Overview

UCSC Blat Alignment
Insertion Location:	intron 25
5' Flanking Sequence:	TACATACATGCAGGCAAAATACTCATACAGTAAAAATTAGAAATTAAGCAAAACCCTAAG TACGTTAAAACATTTTGAGGGTACACAAGTTATCTCTTGCACAGTGCTActag

Gene
***Rat Entrez Gene If Available; Else Human or Mouse

Mouse Allele

MGI	Symbol	Name	Type
MGI:1856917	Dnahc11^iv	situs inversus viscerum	Spontaneous
MGI:3623683	Dnahc11^tm1.1Bknr	targeted mutation 1.1, Martina Brueckner	Targeted (Reporter)
MGI:3623682	Dnahc11^tm1Bknr	targeted mutation 1, Martina Brueckner	Targeted (knock-out)
MGI:2152963	Dnahc11^tm1Ssp	targeted mutation 1, S Steven Potter	Targeted (knock-out)

Associated Diseases

Disease	Disease Class	Sub Category
Ciliary Dyskinesia	Respiratory	Mucosal Inflammation
Kartagener Syndrome	Respiratory	Developmental, Situs Inversus Viscerum

Gene Ontology Function Process Component

GO	Term	Evidence
GO:0000166	nucleotide binding	IEA
GO:0003674	molecular_function	ND
GO:0003777	microtubule motor activity	IEA
GO:0003777	microtubule motor activity	ISS
GO:0004197	cysteine-type endopeptidase activity	IEA
GO:0005524	ATP binding	IEA
GO:0016887	ATPase activity	IEA

Homologene Orthology (Human/Mouse)

Taxon	Symbol	Synonyms	Chromosome
human	DNAH11	CILD7\|DNAHBL\|DNAHC11\|DNHBL\|DPL11\|FLJ30095\|FLJ37699	N/A
mouse	Dnahc11	iv\|lrd	N/A

Related Links

Rat Model Source

Medical College of Wisconsin